Removal of an oral lymphoepithelial cyst: a case report

Authors

  • Maria Eduarda Dias Tavares Faculdade do Amazonas - IAES Author
  • Fernando dos Santos Gonçalves Junior Faculdade do Amazonas - IAES Author
  • Kleber Maia Pereira Faculdade do Amazonas - IAES Author
  • Lara Pepita de Souza Oliveira Faculdade do Amazonas - IAES Author
  • Lizete Karla Filgueiras de Souza Faculdade do Amazonas - IAES Author

DOI:

https://doi.org/10.70614/63r3pd97

Keywords:

Diagnóstico diferencial, Cavidade bucal, Patologia bucal, Biópsia

Abstract

The oral lymphoepithelial cyst (OLC), also referred to as a lymphoid cyst, is an uncommon benign lesion originating from stratified squamous epithelium associated with lymphoid tissue. Its most accepted pathogenesis involves the entrapment of embryonic epithelium within lymphoid aggregates, leading to subsequent proliferation and cystic transformation. Although most frequently reported on the floor of the mouth and the ventral surface of the tongue, it may also occur on the lateral border of the tongue, where its rarity may result in misdiagnosis as other cystic lesions or even neoplastic processes

Downloads

Download data is not yet available.

References

1. Sykara M, Ntovas P, Kalogirou EM, Tosios KI, Sklavounou A. Oral lymphoepithelial cyst: a clinicopathological study of 26 cases and review of the literature. J Clin Exp Dent. 2017;9(8):e1035-43.

2. Huang J, Zhang L, Cheng G, Yang Y. Oral lymphoepithelial cyst at the lateral border of the tongue. Clin Case Rep. 2023;11(9):e7736.

3. Cunha JF, Soares CD, Silveira EJD, Godoy GP, Nonaka CFW, Freitas RDA, et al. Oral lymphoepithelial cyst: a multicenter study of 132 cases in Brazil with clinical, histopathological, and immunohistochemical analyses. Med Oral Patol Oral Cir Bucal. 2022;27(4):e310-6.

4. Carvalho MV, Nonaka CFW, Almeida RAA, Freitas RDA, Miguel MCC, Pinto LP. Cisto linfoepitelial oral: relato de quatro casos e revisão de 119 casos reportados na literatura. J Bras Patol Med Lab. 2012;48(6):449-54.

5. Nakayama Y, Shiba M, Ichihashi Y, Koyama S, Nishikawa Y, Toh Y. Lymphoepithelial cyst on the tongue: a case report. J Oral Biol Craniofac Res. 2023;13(1):74-7.

6. Francisconi CF, Manfrin AR, Ramos LM, da Silva SO, de Aguiar MCF. Oral lymphoepithelial cyst: case report. J Stomatol Oral Maxillofac Surg. 2024;125(1):102-5.

7. Malamed SF. Manual de anestesia local. 6. ed. Rio de Janeiro: Elsevier; 2013.

8. Greenwood M, Lowry J, Rogers S. Oral soft-tissue biopsy: an overview. J Can Dent Assoc. 2013;79:c75.

9. Mohamed F, Patel BC. Oral Surgery, Biopsies. StatPearls. Treasure Island (FL): StatPearls Publishing; 2023 [cited 2025 Oct 1].

10. Leite RB, de Souza LB, Pinto LP, de Medeiros AMC. Oral lymphoepithelial cyst: a case report and literature review. *J Bras Patol Med Lab*. 2017;53(5):334-8.

11. Dominoni CS. Cisto linfoepitelial em língua: relato de caso clínico [Trabalho de Conclusão de Curso]. Campinas (SP): Universidade Estadual de Campinas – Faculdade de Odontologia de Piracicaba; 2024.

12. Galvão, H. C., & Pinto, C. A. (2010). "Cisto linfoepitelial: uma revisão". Revista de Odontologia da UNESP, 39(5), 301-306.

13. Moore RJ, Dave M, Stocker J, Aggarwal VR. Simplifying differential diagnoses of orofacial conditions: a guide to surgical sieves and red flags. Br Dent J. 2021;230(5):289-93. Available from:

14. Wong T, Yap T, Wiesenfeld D. Common benign and malignant oral mucosal disease. Aust J Gen Pract. 2020;49(9):575-80.

15. Hillson R. The surgical sieve revisited: a simple framework for the clinical problem-solver. Clin Teach. 2015;12(2):123-6.

Downloads

Published

2026-02-20

Issue

Vol. 7 No. 2 (2025): Revista Clínica de Odontologia

Section

Relato de Caso

License

Copyright (c) 2026 Revista Clínica de Odontologia

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.